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Full-time PhD-studentship in type 2 diabetes related studies

University of Roehampton

Requisitos

  • Applicants should have the equivalent of a UK 2.1 honours degree or higher and a relevant MSc or MRes qualification in a biology-related subject.

Descripción


The University of Roehampton is offering a Three-year, full-time PhD-studentship in Intercellular communication and pancreatic islet function in type 2 diabetes. This fully funded scholarship will cover home/EU fees of £4,121 for Home/EU students and maintenance of £16,296 p.a. in 2016/17 for 3 years full-time and laboratory costs. Deadline is due 18 July 2016.

 

Project description:

The International Diabetes Federation (IDF) has predicted that 642 million people will have diabetes by 2040, which will be over double the figure for 2000. The majority of these individuals have Type 2 diabetes which occurs under conditions of insulin resistance coupled with pancreatic beta-cell failure and is often associated with obesity. Understanding pancreatic islet function is essential for identifying the underlying disorder(s) in Type 2 diabetes and for identifying appropriate targets for novel therapeutic intervention.

The islet is a complex organ consisting of different cell types in addition to insulin-producing beta cells. Our studies have previously shown that intercellular communication within the islets is paramount for the normal physiological release of insulin and recent findings in Dr Hauge Evans’ lab suggest that interactions between islet cells are also important for beta cell survival under stressful conditions such as those seen in the development of type 2 diabetes. The aim of the proposed research is to further identify and describe the underlying cellular and molecular mechanisms conveying these effects with particular focus on the role of the islet peptides somatostatin and ghrelin.

The experimental models used in this project will include pancreatic cell lines and primary mouse islets and physiological function will be assessed by a number of cell biology, molecular biology and biochemistry techniques, which are available within the modern labs of the Department of Life Sciences at the University of Roehampton. These include cell and primary tissue culture, static and dynamic secretion experiments, immunohistochemistry, radioimmunoassay, flow cytometry, DNA/RNA extraction and purification, mRNA reverse transcription, qPCR, siRNA knockdown of gene expression, western blotting, apoptosis and proliferation assays.

Funding:

Funding is available for UK/EU and International* students at Home/EU rates for three years full-time study. This fully funded scholarship will cover home/EU fees of £4,121 for Home/EU students and maintenance of £16,296 p.a. in 2016/17 for 3 years full-time and laboratory costs.

*(see end note)

 

Eligibility and how to apply:

Applicants should have the equivalent of a UK 2.1 honours degree or higher and a relevant MSc or MRes qualification in a biology-related subject.

The successful candidate should be available to start on 1st October 2016

To apply, please email the following to pgresearch@roehampton.ac.ukwith the subject heading “Intercellular communication and pancreatic islet function”.

  1. A copy of your CV including copies of your academic qualifications.
  2. Contact details of two academic referees.
  3. Official academic transcripts.
  4. Personal statement outlining your suitability for the studentship, what you hope to achieve from the PhD and your research experience to date.

 

The closing date for completed applications is:                   18 July 2016.

Formal interviews are expected to take place:                     5  August 2016.

 

Further information:

For informal enquiries please contact Dr Astrid Hauge Evans (Astrid.Hauge-evans@roehampton.ac.uk). For additional information on Dr Hauge Evans’ research activities please acces his contact information on Roehampton's web page. 

 

*Recipients of these studentships will be covered for Home/EU fees, and recipients due to pay overseas fees will be required to pay the difference between Home/EU and overseas tuition fee rates.


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Cómo solicitar

Plazo
Desde 2016-07-06 00:00:00.0 hasta 2016-07-18 00:00:00.0
Fecha de convocatoria
2016-07-06 00:00:00.0
Información del convocante
University of Roehampton
Roehampton Ln
SW15 5PU
Web
http://www.roehampton.ac.uk/home/
Email de contacto
enquiries@roehampton.ac.uk
Teléfono
+44 (0)20 8392 3232
Fax
+44 (0)20 8392 3470
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